BindingDB PrimarySearch

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SMILES: N[C@@H]1C[C@H]1c1ccc(cc1)-c1cccc(O)c1

InChI Key: InChIKey=DSOJSZXQRJGBCW-LSDHHAIUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50445349
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
ORYZON GENOMICS, S.A. US Patent					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant LSD1 using dimethylated H3K4 peptide as substrate after 1 hr				J Med Chem 56: 9496-508 (2014) Article DOI: 10.1021/jm400870h BindingDB Entry DOI: 10.7270/Q2Z60QJ7
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50445349 (CHEMBL3104261 \| US9676701, 63 Enantiomers of 4R...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem		n/a	n/a	4.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair