BDBM50445407 CHEMBL3104662

SMILES: CCCC1SC(NC1=O)=Cc1nc2c(C)cccc2[nH]1

InChI Key: InChIKey=LXEOJPACYKDYGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50445407 (CHEMBL3104662) Show SMILES CCCC1SC(NC1=O)=Cc1nc2c(C)cccc2[nH]1 |w:9.10| Show InChI InChI=1S/C15H17N3OS/c1-3-5-11-15(19)18-13(20-11)8-12-16-10-7-4-6-9(2)14(10)17-12/h4,6-8,11H,3,5H2,1-2H3,(H,16,17)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay				Eur J Med Chem 71: 250-8 (2014) Article DOI: 10.1016/j.ejmech.2013.10.075 BindingDB Entry DOI: 10.7270/Q2F76F15
					More data for this Ligand-Target Pair