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SMILES: CN1CCN(CC1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1

InChI Key: InChIKey=SDQYFXSCVGEULC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445525   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))		BDBM50445525
PNG
(CHEMBL3103030)
Show SMILES CN1CCN(CC1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1
Show InChI InChI=1S/C20H22N4O/c1-15-4-3-5-17(12-15)24-14-21-18-13-16(6-7-19(18)24)20(25)23-10-8-22(2)9-11-23/h3-7,12-14H,8-11H2,1-2H3
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MMDB

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Article
PubMed
n/an/a 2.71E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay

Bioorg Med Chem Lett 24: 630-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H
More data for this
Ligand-Target Pair