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SMILES: Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCC(CC1)C(F)(F)F

InChI Key: InChIKey=XCTBKOKQGKOMSM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445531   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))		BDBM50445531
PNG
(CHEMBL3103024)
Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCC(CC1)C(F)(F)F
Show InChI InChI=1S/C21H20F3N3O/c1-14-3-2-4-17(11-14)27-13-25-18-12-15(5-6-19(18)27)20(28)26-9-7-16(8-10-26)21(22,23)24/h2-6,11-13,16H,7-10H2,1H3
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PubMed
n/an/a 1.52E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay

Bioorg Med Chem Lett 24: 630-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H
More data for this
Ligand-Target Pair