BDBM50445564 CHEMBL3103256

SMILES: CC(=O)N(O)CC=CP(O)([O-])=O

InChI Key: InChIKey=LJCWFOKLHHHANO-UHFFFAOYSA-M

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (Plasmodium falciparum (isolate 3D7))	BDBM50445564 (CHEMBL3103256) Show SMILES CC(=O)N(O)CC=CP(O)([O-])=O |w:6.5| Show InChI InChI=1S/C5H10NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h2,4,8H,3H2,1H3,(H2,9,10,11)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometry				J Med Chem 61: 8847-8858 (2018) Article DOI: 10.1021/acs.jmedchem.8b01026 BindingDB Entry DOI: 10.7270/Q2S75JZ7
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis)	BDBM50445564 (CHEMBL3103256) Show SMILES CC(=O)N(O)CC=CP(O)([O-])=O |w:6.5| Show InChI InChI=1S/C5H10NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h2,4,8H,3H2,1H3,(H2,9,10,11)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Dxr				Bioorg Med Chem Lett 24: 649-53 (2014) Article DOI: 10.1016/j.bmcl.2013.11.067 BindingDB Entry DOI: 10.7270/Q24Q7WGS
					More data for this Ligand-Target Pair