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SMILES: CC(=O)c1nnn(c1C)-c1cnn(-c2ccccc2)c(=O)c1I

InChI Key: InChIKey=PJWUWMOPOGKXLY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445937   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3


(Homo sapiens (Human))		BDBM50445937
PNG
(CHEMBL3105845)
Show SMILES CC(=O)c1nnn(c1C)-c1cnn(-c2ccccc2)c(=O)c1I
Show InChI InChI=1S/C15H12IN5O2/c1-9-14(10(2)22)18-19-20(9)12-8-17-21(15(23)13(12)16)11-6-4-3-5-7-11/h3-8H,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged PFKFB3 expressed in Escherichia coli BL21(DE3) using fructose 6-phosphate as substrate preincubated for 30...

Bioorg Med Chem 22: 1029-39 (2014)


Article DOI: 10.1016/j.bmc.2013.12.041
BindingDB Entry DOI: 10.7270/Q2TB18C4
More data for this
Ligand-Target Pair