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SMILES: CC(C)N(C(C)C)C(=O)c1cccc2C=Cc3ccccc3Nc12

InChI Key: InChIKey=SBIHJHKRTVMJKT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446059   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 4


(Homo sapiens (Human))		BDBM50446059
PNG
(CHEMBL3103386)
Show SMILES CC(C)N(C(C)C)C(=O)c1cccc2C=Cc3ccccc3Nc12 |c:14|
Show InChI InChI=1S/C21H24N2O/c1-14(2)23(15(3)4)21(24)18-10-7-9-17-13-12-16-8-5-6-11-19(16)22-20(17)18/h5-15,22H,1-4H3
KEGG

UniProtKB/SwissProt

DrugBank
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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.06E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...

Bioorg Med Chem 22: 1077-88 (2014)


Article DOI: 10.1016/j.bmc.2013.12.035
BindingDB Entry DOI: 10.7270/Q21R6S09
More data for this
Ligand-Target Pair