BDBM50446184 CHEMBL3109014

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CCC2)c2ccccc12

InChI Key: InChIKey=IZHPVQBSCBLDJU-NHTNDUFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50446184 (CHEMBL3109014) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CCC2)c2ccccc12 |r| Show InChI InChI=1S/C25H29NO5/c27-14-21-22(28)23(29)24(30)25(31-21)26-13-18(19-6-1-2-7-20(19)26)12-15-8-10-17(11-9-15)16-4-3-5-16/h1-2,6-11,13,16,21-25,27-30H,3-5,12,14H2/t21-,22-,23+,24-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...				ACS Med Chem Lett 5: 51-5 (2014) Article DOI: 10.1021/ml400339b BindingDB Entry DOI: 10.7270/Q24J0GM7
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