BDBM50446311 CHEMBL3109351

SMILES: COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@@H]3CNC[C@H]3OC)c2n1

InChI Key: InChIKey=NQOAYTFDSNONAL-FGZHOGPDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50446311 (CHEMBL3109351) Show SMILES COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@@H]3CNC[C@H]3OC)c2n1 |r| Show InChI InChI=1S/C24H26N4O4/c1-29-10-11-31-17-8-9-28-19(13-26-23(28)12-17)18-7-6-16-4-3-5-20(24(16)27-18)32-22-15-25-14-21(22)30-2/h3-9,12-13,21-22,25H,10-11,14-15H2,1-2H3/t21-,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of cFMS (unknown origin)				ACS Med Chem Lett 5: 78-83 (2014) Article DOI: 10.1021/ml4003953 BindingDB Entry DOI: 10.7270/Q23N24VQ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50446311 (CHEMBL3109351) Show SMILES COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@@H]3CNC[C@H]3OC)c2n1 |r| Show InChI InChI=1S/C24H26N4O4/c1-29-10-11-31-17-8-9-28-19(13-26-23(28)12-17)18-7-6-16-4-3-5-20(24(16)27-18)32-22-15-25-14-21(22)30-2/h3-9,12-13,21-22,25H,10-11,14-15H2,1-2H3/t21-,22-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...				ACS Med Chem Lett 5: 78-83 (2014) Article DOI: 10.1021/ml4003953 BindingDB Entry DOI: 10.7270/Q23N24VQ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50446311 (CHEMBL3109351) Show SMILES COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@@H]3CNC[C@H]3OC)c2n1 |r| Show InChI InChI=1S/C24H26N4O4/c1-29-10-11-31-17-8-9-28-19(13-26-23(28)12-17)18-7-6-16-4-3-5-20(24(16)27-18)32-22-15-25-14-21(22)30-2/h3-9,12-13,21-22,25H,10-11,14-15H2,1-2H3/t21-,22-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...				ACS Med Chem Lett 5: 78-83 (2014) Article DOI: 10.1021/ml4003953 BindingDB Entry DOI: 10.7270/Q23N24VQ
					More data for this Ligand-Target Pair