BDBM50446355 CHEMBL3109618

SMILES: Cc1nc2cc(NC(c3c(C)[nH]c4ccccc34)c3ccccc3Cl)ccc2s1

InChI Key: InChIKey=GCSKLLBVPVSKGW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50446355 (CHEMBL3109618) Show SMILES Cc1nc2cc(NC(c3c(C)[nH]c4ccccc34)c3ccccc3Cl)ccc2s1 Show InChI InChI=1S/C24H20ClN3S/c1-14-23(18-8-4-6-10-20(18)26-14)24(17-7-3-5-9-19(17)25)28-16-11-12-22-21(13-16)27-15(2)29-22/h3-13,24,26,28H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assay				ACS Med Chem Lett 5: 199-204 (2014) Article DOI: 10.1021/ml400462j BindingDB Entry DOI: 10.7270/Q2KK9D8Q
					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50446355 (CHEMBL3109618) Show SMILES Cc1nc2cc(NC(c3c(C)[nH]c4ccccc34)c3ccccc3Cl)ccc2s1 Show InChI InChI=1S/C24H20ClN3S/c1-14-23(18-8-4-6-10-20(18)26-14)24(17-7-3-5-9-19(17)25)28-16-11-12-22-21(13-16)27-15(2)29-22/h3-13,24,26,28H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...				ACS Med Chem Lett 5: 199-204 (2014) Article DOI: 10.1021/ml400462j BindingDB Entry DOI: 10.7270/Q2KK9D8Q
					More data for this Ligand-Target Pair