BDBM50446375 CHEMBL3109612

SMILES: Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1nccn1C

InChI Key: InChIKey=YAWYKJFTXCRSSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50446375 (CHEMBL3109612) Show SMILES Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1nccn1C Show InChI InChI=1S/C20H19ClN4/c1-13-18(16-5-3-4-6-17(16)23-13)19(20-22-11-12-25(20)2)24-15-9-7-14(21)8-10-15/h3-12,19,23-24H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assay				ACS Med Chem Lett 5: 199-204 (2014) Article DOI: 10.1021/ml400462j BindingDB Entry DOI: 10.7270/Q2KK9D8Q
					More data for this Ligand-Target Pair