BDBM50446391 CHEMBL3109625

SMILES: COc1cc2N=C(N)C3(CCC3)c2cc1OC

InChI Key: InChIKey=ZUCBRYGODKLTPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein G9a (G9a) (Homo sapiens (Human))	BDBM50446391 (CHEMBL3109625) Show SMILES COc1cc2N=C(N)C3(CCC3)c2cc1OC |t:5| Show InChI InChI=1S/C13H16N2O2/c1-16-10-6-8-9(7-11(10)17-2)15-12(14)13(8)4-3-5-13/h6-7H,3-5H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin) using biotinylated-histone H3(1-21) peptide as substrate after 3 hrs by AlphaLISA assay				ACS Med Chem Lett 5: 205-9 (2014) Article DOI: 10.1021/ml400496h BindingDB Entry DOI: 10.7270/Q2FT8NJ0
					More data for this Ligand-Target Pair