null

SMILES: COC(=O)[C@H]1CCCN1C(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=LKPDYIDWRMNYMP-HXUWFJFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50446682 (CHEMBL3113616) Show SMILES COC(=O)[C@H]1CCCN1C(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C23H22N2O6S/c1-15-9-11-16(12-10-15)32(29,30)25-14-18(17-6-3-4-7-19(17)25)21(26)22(27)24-13-5-8-20(24)23(28)31-2/h3-4,6-7,9-12,14,20H,5,8,13H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guru Nanak Dev University Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometry				Bioorg Med Chem 22: 1642-8 (2014) Article DOI: 10.1016/j.bmc.2014.01.027 BindingDB Entry DOI: 10.7270/Q2KH0PT3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50446682 (CHEMBL3113616) Show SMILES COC(=O)[C@H]1CCCN1C(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C23H22N2O6S/c1-15-9-11-16(12-10-15)32(29,30)25-14-18(17-6-3-4-7-19(17)25)21(26)22(27)24-13-5-8-20(24)23(28)31-2/h3-4,6-7,9-12,14,20H,5,8,13H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Guru Nanak Dev University Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIA				Bioorg Med Chem 22: 1642-8 (2014) Article DOI: 10.1016/j.bmc.2014.01.027 BindingDB Entry DOI: 10.7270/Q2KH0PT3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50446682 (CHEMBL3113616) Show SMILES COC(=O)[C@H]1CCCN1C(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C23H22N2O6S/c1-15-9-11-16(12-10-15)32(29,30)25-14-18(17-6-3-4-7-19(17)25)21(26)22(27)24-13-5-8-20(24)23(28)31-2/h3-4,6-7,9-12,14,20H,5,8,13H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Guru Nanak Dev University Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIA in presence of pig liver esterase				Bioorg Med Chem 22: 1642-8 (2014) Article DOI: 10.1016/j.bmc.2014.01.027 BindingDB Entry DOI: 10.7270/Q2KH0PT3
					More data for this Ligand-Target Pair