BDBM50446880 CHEMBL3115286

SMILES: Cc1c(C)n(Cc2ccccc2)c(=O)c(C(=O)NCC(O)=O)c1O

InChI Key: InChIKey=HMAUHOQJEUNTGR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50446880 (CHEMBL3115286) Show SMILES Cc1c(C)n(Cc2ccccc2)c(=O)c(C(=O)NCC(O)=O)c1O Show InChI InChI=1S/C17H18N2O5/c1-10-11(2)19(9-12-6-4-3-5-7-12)17(24)14(15(10)22)16(23)18-8-13(20)21/h3-7,22H,8-9H2,1-2H3,(H,18,23)(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISA				J Med Chem 56: 9369-402 (2014) Article DOI: 10.1021/jm400386j BindingDB Entry DOI: 10.7270/Q290258T
					More data for this Ligand-Target Pair