BindingDB logo
myBDB logout

null

SMILES: Clc1ccc(cc1)C(NCc1ccccc1)c1ccc(cc1)-c1ccncc1

InChI Key: InChIKey=QCOQDZLFGQZWGN-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447168   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50447168
PNG
(CHEMBL3113139)
Show SMILES Clc1ccc(cc1)C(NCc1ccccc1)c1ccc(cc1)-c1ccncc1
Show InChI InChI=1S/C25H21ClN2/c26-24-12-10-23(11-13-24)25(28-18-19-4-2-1-3-5-19)22-8-6-20(7-9-22)21-14-16-27-17-15-21/h1-17,25,28H,18H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.25E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...

Eur J Med Chem 73: 167-76 (2014)


Article DOI: 10.1016/j.ejmech.2013.11.036
BindingDB Entry DOI: 10.7270/Q2BR8TNS
More data for this
Ligand-Target Pair