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SMILES: Clc1ccc(cc1)C(NC1CCCCC1)c1ccc(cc1)-c1ccncc1

InChI Key: InChIKey=PYKLZPJFIKUEJF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447169   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50447169
PNG
(CHEMBL3113137)
Show SMILES Clc1ccc(cc1)C(NC1CCCCC1)c1ccc(cc1)-c1ccncc1
Show InChI InChI=1S/C24H25ClN2/c25-22-12-10-21(11-13-22)24(27-23-4-2-1-3-5-23)20-8-6-18(7-9-20)19-14-16-26-17-15-19/h6-17,23-24,27H,1-5H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...

Eur J Med Chem 73: 167-76 (2014)


Article DOI: 10.1016/j.ejmech.2013.11.036
BindingDB Entry DOI: 10.7270/Q2BR8TNS
More data for this
Ligand-Target Pair