BDBM50447172 CHEMBL3113134

SMILES: CC(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ccncc1

InChI Key: InChIKey=OWJDEPLXSNLLNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50447172 (CHEMBL3113134) Show SMILES CC(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C21H21ClN2/c1-15(2)24-21(19-7-9-20(22)10-8-19)18-5-3-16(4-6-18)17-11-13-23-14-12-17/h3-15,21,24H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair