null

SMILES: Cn1cnc(c1)S(=O)(=O)N1CC2CCC(NC(=O)C3CCCCC3)C2C1

InChI Key: InChIKey=DXIVVDJFDWAREB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50448004 (CHEMBL3115230) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CC2CCC(NC(=O)C3CCCCC3)C2C1 Show InChI InChI=1S/C18H28N4O3S/c1-21-11-17(19-12-21)26(24,25)22-9-14-7-8-16(15(14)10-22)20-18(23)13-5-3-2-4-6-13/h11-16H,2-10H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT1 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50448004 (CHEMBL3115230) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CC2CCC(NC(=O)C3CCCCC3)C2C1 Show InChI InChI=1S/C18H28N4O3S/c1-21-11-17(19-12-21)26(24,25)22-9-14-7-8-16(15(14)10-22)20-18(23)13-5-3-2-4-6-13/h11-16H,2-10H2,1H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT2 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
					More data for this Ligand-Target Pair