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SMILES: CNc1nc(Nc2cn(nc2C)C(C)(C)C(=O)NC(C)C)ncc1C(F)(F)F

InChI Key: InChIKey=KYZGPONBRQRHNZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448120   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM50448120
PNG
(CHEMBL3122111)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)C(=O)NC(C)C)ncc1C(F)(F)F
Show InChI InChI=1S/C17H24F3N7O/c1-9(2)23-14(28)16(4,5)27-8-12(10(3)26-27)24-15-22-7-11(17(18,19)20)13(21-6)25-15/h7-9H,1-6H3,(H,23,28)(H2,21,22,24,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assay

J Med Chem 57: 921-36 (2014)


Article DOI: 10.1021/jm401654j
BindingDB Entry DOI: 10.7270/Q2N0181N
More data for this
Ligand-Target Pair