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SMILES: CN1N=C(C2CC2C1=O)c1ccc(OC2CCN(CC2)C2CCCC2)cc1

InChI Key: InChIKey=JFRUETNFZHUWLL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448285   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50448285
PNG
(CHEMBL3121093)
Show SMILES CN1N=C(C2CC2C1=O)c1ccc(OC2CCN(CC2)C2CCCC2)cc1 |c:2|
Show InChI InChI=1S/C22H29N3O2/c1-24-22(26)20-14-19(20)21(23-24)15-6-8-17(9-7-15)27-18-10-12-25(13-11-18)16-4-2-3-5-16/h6-9,16,18-20H,2-5,10-14H2,1H3
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Article
PubMed
 5.70n/an/an/an/an/an/an/an/a



Teva Pharmaceutical Global R&D

Curated by ChEMBL


Assay Description
Displacement of [3H]NAMH from rat histamine H3 receptor transfected in CHO cells

Bioorg Med Chem Lett 24: 1303-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.01.061
BindingDB Entry DOI: 10.7270/Q2Z89DXJ
More data for this
Ligand-Target Pair