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SMILES: C[C@H]1C\C(C)=C\C=C/C(=O)O[C@@H](Cc2nc(CCCCC(=O)O1)cs2)\C=C(/C)\C=C\C(\C)=C\CN(C)C

InChI Key: InChIKey=VSVORQIMRUVRPE-MMPYLIGOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448482   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase subunit gamma-1


(Homo sapiens (Human))		BDBM50448482
PNG
(CHEMBL3126408)
Show SMILES C[C@H]1C\C(C)=C\C=C/C(=O)O[C@@H](Cc2nc(CCCCC(=O)O1)cs2)\C=C(/C)\C=C\C(\C)=C\CN(C)C |r,c:6,t:4|
Show InChI InChI=1S/C30H42N2O4S/c1-22(16-17-32(5)6)14-15-24(3)19-27-20-28-31-26(21-37-28)11-7-8-12-29(33)35-25(4)18-23(2)10-9-13-30(34)36-27/h9-10,13-16,19,21,25,27H,7-8,11-12,17-18,20H2,1-6H3/b13-9-,15-14+,22-16+,23-10+,24-19+/t25-,27+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



St. John's University

Curated by ChEMBL


Assay Description
Inhibition of DNA polymerase-gamma (unknown origin) assessed as incorporation of Br(d)UTP by colorimetric analysis

Bioorg Med Chem 22: 116-25 (2013)


Article DOI: 10.1016/j.bmc.2013.11.046
BindingDB Entry DOI: 10.7270/Q23T9JQ8
More data for this
Ligand-Target Pair