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BDBM50449324 CHEMBL3126042

SMILES: Fc1cc(F)cc(c1)-c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)N2CCOC2=O)nc1

InChI Key: InChIKey=YPQQARNVJDILSU-QGGXVJLZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449324   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50449324
PNG
(CHEMBL3126042)
Show SMILES Fc1cc(F)cc(c1)-c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)N2CCOC2=O)nc1 |r,wU:15.15,18.22,(16.56,-26.33,;17.33,-24.99,;16.56,-23.66,;17.33,-22.33,;16.56,-21,;18.87,-22.33,;19.64,-23.66,;18.87,-24.99,;21.18,-23.66,;21.95,-22.33,;23.49,-22.33,;24.26,-23.66,;25.8,-23.66,;26.57,-24.99,;25.8,-26.33,;28.11,-24.99,;28.88,-26.33,;30.42,-26.33,;31.19,-24.99,;30.42,-23.66,;28.88,-23.66,;32.73,-24.99,;33.63,-26.24,;35.1,-25.76,;35.1,-24.22,;33.63,-23.75,;33.15,-22.29,;23.49,-24.99,;21.95,-24.99,)|
Show InChI InChI=1S/C21H21F2N3O3/c22-16-9-15(10-17(23)11-16)14-3-6-19(24-12-14)25-20(27)13-1-4-18(5-2-13)26-7-8-29-21(26)28/h3,6,9-13,18H,1-2,4-5,7-8H2,(H,24,25,27)/t13-,18+
KEGG

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Article
PubMed
 8n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation counting

Bioorg Med Chem Lett 24: 1458-61 (2014)


Article DOI: 10.1016/j.bmcl.2014.02.023
BindingDB Entry DOI: 10.7270/Q2S75HT1
More data for this
Ligand-Target Pair