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BDBM50449604 CHEMBL4175374

SMILES: CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OCCCN3CCOCC3)ccc2n1

InChI Key: InChIKey=GBCNIHVJHDAKGF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449604   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein norA


(Staphylococcus aureus)		BDBM50449604
PNG
(CHEMBL4175374)
Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OCCCN3CCOCC3)ccc2n1
Show InChI InChI=1S/C32H43N3O4/c1-2-19-37-27-9-7-26(8-10-27)31-25-32(39-23-18-34-13-4-3-5-14-34)29-24-28(11-12-30(29)33-31)38-20-6-15-35-16-21-36-22-17-35/h7-12,24-25H,2-6,13-23H2,1H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



University of Perugia

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay

Eur J Med Chem 155: 428-433 (2018)


Article DOI: 10.1016/j.ejmech.2018.06.013
BindingDB Entry DOI: 10.7270/Q2XP77H5
More data for this
Ligand-Target Pair