BDBM50449645 AF-102B::CHEMBL2021361::FKS-508::SND-5008::SNI-2011::SNK-508

SMILES: C[C@H]1OC2(CS1)CN1CCC2CC1

InChI Key: InChIKey=WUTYZMFRCNBCHQ-PEHGTWAWSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50449645 (AF-102B | CHEMBL2021361 | FKS-508 | SND-5008 | SNI...) Show SMILES C[C@H]1OC2(CS1)CN1CCC2CC1 |r,wD:1.0,(26.77,-12.75,;25.3,-13.54,;24.07,-12.62,;22.81,-13.51,;23.3,-15.01,;24.79,-15.01,;22.81,-11.93,;21.47,-11.16,;20.92,-12.45,;22.01,-13.12,;21.47,-14.28,;20.15,-13.51,;20.15,-11.98,)| Show InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50449645 (AF-102B | CHEMBL2021361 | FKS-508 | SND-5008 | SNI...) Show SMILES C[C@H]1OC2(CS1)CN1CCC2CC1 |r,wD:1.0,(26.77,-12.75,;25.3,-13.54,;24.07,-12.62,;22.81,-13.51,;23.3,-15.01,;24.79,-15.01,;22.81,-11.93,;21.47,-11.16,;20.92,-12.45,;22.01,-13.12,;21.47,-14.28,;20.15,-13.51,;20.15,-11.98,)| Show InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair