BDBM50449818 CHEMBL4165896

SMILES: COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O

InChI Key: InChIKey=HPOYDHZZGCZYRF-UHFFFAOYSA-N

Data: 48 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 50449818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant full-length human carbonic anhydrase 2 expressed in Escherichia coli in presence of ANS by fluorescent thermal shift ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 14 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 5B (40 to 317 residues) expressed in Escherichia coli Rosetta 2 (DE3)...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase III (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 (4 to 260 residues) expressed in Escherichia coli BL21 (DE3) strain assessed as intrinsic ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 (19 to 284 residues) expressed in mammalian expression system in presence of ANS by fluore...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 (30 to 291 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain assessed as int...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIV (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 14 (20 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli in presence of ANS by fluorescent thermal shift assay				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 5B (40 to 317 residues) expressed in Escherichia coli Rosetta 2 (DE3)...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 (38 to 414 residues) expressed in 293-F cells assessed as intrinsic Kd in presence of ANS ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase III (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 (4 to 260 residues) expressed in Escherichia coli BL21 (DE3) strain in presence of ANS by ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His-tagged human carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) strain ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant C-terminal His6-tagged full-length human carbonic anhydrase 5A expressed in Escherichia coli BL21 (DE3) strain in pre...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (CA XIII) (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 (1 to 262 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain assessed as intr...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 (38 to 414 residues) expressed in 293-F cells in presence of ANS by fluorescent thermal sh...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 (30 to 291 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain in presence of ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His-tagged human carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) strain ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIV (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 14 (20 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli assessed as intrinsic Kd in presence of ANS by fluorescent t...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant full-length human carbonic anhydrase 2 expressed in Escherichia coli assessed as intrinsic Kd in presence of ANS by f...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (CA XIII) (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 (1 to 262 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain in presence of A...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant C-terminal His6-tagged full-length human carbonic anhydrase 5A expressed in Escherichia coli BL21 (DE3) strain assess...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 (19 to 284 residues) expressed in mammalian expression system assessed as intrinsic Kd in ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 7 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5a expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 14 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 expressed in mammalian cell expression system assessed as kinetic dissociation constant fl...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 2 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 7 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 expressed in mammalian cell expression system assessed as observed dissociation constant f...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 2 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5a expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
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Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human))	BDBM50449818 (CHEMBL4165896) Show SMILES COC(=O)CCCNC(=O)c1cc(c(Cl)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C12H14Cl2N2O5S/c1-21-11(17)3-2-4-16-12(18)7-5-10(22(15,19)20)9(14)6-8(7)13/h5-6H,2-4H2,1H3,(H,16,18)(H2,15,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair