BDBM50449821 CHEMBL4168586

SMILES: NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl

InChI Key: InChIKey=AZHHAHHRNOQVSO-UHFFFAOYSA-N

Data: 47 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 50449821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 (19 to 284 residues) expressed in mammalian expression system in presence of ANS by fluore...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIV (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 14 (20 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 5B (40 to 317 residues) expressed in Escherichia coli Rosetta 2 (DE3)...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 (30 to 291 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain assessed as int...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 6 (21 to 290 residues) expressed in Escherichia coli Rosetta 2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant C-terminal His6-tagged full-length human carbonic anhydrase 5A expressed in Escherichia coli BL21 (DE3) strain assess...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 5B (40 to 317 residues) expressed in Escherichia coli Rosetta 2 (DE3)...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant full-length human carbonic anhydrase 2 expressed in Escherichia coli in presence of ANS by fluorescent thermal shift ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His-tagged human carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) strain ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant C-terminal His6-tagged full-length human carbonic anhydrase 5A expressed in Escherichia coli BL21 (DE3) strain in pre...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 (38 to 414 residues) expressed in 293-F cells in presence of ANS by fluorescent thermal sh...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His-tagged human carbonic anhydrase 7 (3 to 264 residues) expressed in Escherichia coli BL21 (DE3) strain ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli in presence of ANS by fluorescent thermal shift assay				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase III (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.55E+4	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 (4 to 260 residues) expressed in Escherichia coli BL21 (DE3) strain in presence of ANS by ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (CA XIII) (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	667	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 (1 to 262 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain in presence of A...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIV (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant N-terminal His6-tagged human carbonic anhydrase 14 (20 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli assessed as intrinsic Kd in presence of ANS by fluorescent t...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 (30 to 291 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain in presence of ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (CA XIII) (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 (1 to 262 residues) expressed in Escherichia coli Rosetta 2 (DE3) strain assessed as intr...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant full-length human carbonic anhydrase 2 expressed in Escherichia coli assessed as intrinsic Kd in presence of ANS by f...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic Anhydrase III (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 (4 to 260 residues) expressed in Escherichia coli BL21 (DE3) strain assessed as intrinsic ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 (19 to 284 residues) expressed in mammalian expression system assessed as intrinsic Kd in ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 expressed in mammalian cell expression system assessed as observed dissociation constant f...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5a expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 2 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 13 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 14 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 7 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 2 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5a expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 1 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 14 expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase V (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as kinetic dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 3 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 12 expressed in Escherichia coli expression system assessed as observed dissociation constan...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 7 expressed in Escherichia coli expression system assessed as observed dissociation constant...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 6 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 4 expressed in Escherichia coli expression system assessed as kinetic dissociation constant ...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 expressed in mammalian cell expression system assessed as kinetic dissociation constant fl...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111825
					More data for this Ligand-Target Pair
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM50449821 (CHEMBL4168586) Show SMILES NS(=O)(=O)c1cc(C(=O)NCCCC(O)=O)c(Cl)cc1Cl Show InChI InChI=1S/C11H12Cl2N2O5S/c12-7-5-8(13)9(21(14,19)20)4-6(7)11(18)15-3-1-2-10(16)17/h4-5H,1-3H2,(H,15,18)(H,16,17)(H2,14,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
Vilnius University Curated by ChEMBL					Assay Description Binding affinity to recombinant human carbonic anhydrase 9 (38 to 414 residues) expressed in 293-F cells assessed as intrinsic Kd in presence of ANS ...				Eur J Med Chem 156: 61-78 (2018) Article DOI: 10.1016/j.ejmech.2018.06.059 BindingDB Entry DOI: 10.7270/Q2805559
					More data for this Ligand-Target Pair