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SMILES: Cc1nn(-c2ccc(F)cc2)c(=O)c2nocc12

InChI Key: InChIKey=VDZKRKYRGLTAQL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450059   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50450059
PNG
(CHEMBL4160584)
Show SMILES Cc1nn(-c2ccc(F)cc2)c(=O)c2nocc12
Show InChI InChI=1S/C12H8FN3O2/c1-7-10-6-18-15-11(10)12(17)16(14-7)9-4-2-8(13)3-5-9/h2-6H,1H3
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PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of Montana

Curated by ChEMBL


Assay Description
Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method

Bioorg Med Chem 26: 4797-4803 (2018)


Article DOI: 10.1016/j.bmc.2018.08.012
BindingDB Entry DOI: 10.7270/Q2Q242TX
More data for this
Ligand-Target Pair