null

SMILES: Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3cc(F)ccc3F)cc12

InChI Key: InChIKey=UDONKWVUKRXGRH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50450217 (CHEMBL4164769) Show SMILES Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3cc(F)ccc3F)cc12 Show InChI InChI=1S/C22H16F2N2O4/c1-26-19-11-16(30-20-10-14(23)5-7-17(20)24)6-8-18(19)25-21(26)12-29-15-4-2-3-13(9-15)22(27)28/h2-11H,12H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 26: 5079-5098 (2018) Article DOI: 10.1016/j.bmc.2018.09.006 BindingDB Entry DOI: 10.7270/Q2J968XC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50450217 (CHEMBL4164769) Show SMILES Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3cc(F)ccc3F)cc12 Show InChI InChI=1S/C22H16F2N2O4/c1-26-19-11-16(30-20-10-14(23)5-7-17(20)24)6-8-18(19)25-21(26)12-29-15-4-2-3-13(9-15)22(27)28/h2-11H,12H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 26: 5079-5098 (2018) Article DOI: 10.1016/j.bmc.2018.09.006 BindingDB Entry DOI: 10.7270/Q2J968XC
					More data for this Ligand-Target Pair