null

SMILES: Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3ccc(F)cc3)cc12

InChI Key: InChIKey=OCHMHCSHKCGIDN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50450225 (CHEMBL4172725) Show SMILES Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3ccc(F)cc3)cc12 Show InChI InChI=1S/C22H17FN2O4/c1-25-20-12-18(29-16-7-5-15(23)6-8-16)9-10-19(20)24-21(25)13-28-17-4-2-3-14(11-17)22(26)27/h2-12H,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 26: 5079-5098 (2018) Article DOI: 10.1016/j.bmc.2018.09.006 BindingDB Entry DOI: 10.7270/Q2J968XC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50450225 (CHEMBL4172725) Show SMILES Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3ccc(F)cc3)cc12 Show InChI InChI=1S/C22H17FN2O4/c1-25-20-12-18(29-16-7-5-15(23)6-8-16)9-10-19(20)24-21(25)13-28-17-4-2-3-14(11-17)22(26)27/h2-12H,13H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 26: 5079-5098 (2018) Article DOI: 10.1016/j.bmc.2018.09.006 BindingDB Entry DOI: 10.7270/Q2J968XC
					More data for this Ligand-Target Pair