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SMILES: Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3cccc(F)c3F)cc12

InChI Key: InChIKey=JXNNRUVERHNPNG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450228   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50450228
PNG
(CHEMBL4161352)
Show SMILES Cn1c(COc2cccc(c2)C(O)=O)nc2ccc(Oc3cccc(F)c3F)cc12
Show InChI InChI=1S/C22H16F2N2O4/c1-26-18-11-15(30-19-7-3-6-16(23)21(19)24)8-9-17(18)25-20(26)12-29-14-5-2-4-13(10-14)22(27)28/h2-11H,12H2,1H3,(H,27,28)
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n/an/an/an/a 230n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay

Bioorg Med Chem 26: 5079-5098 (2018)


Article DOI: 10.1016/j.bmc.2018.09.006
BindingDB Entry DOI: 10.7270/Q2J968XC
More data for this
Ligand-Target Pair