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SMILES: Cl.Cl.Cc1cc(Oc2ccc3nc(COc4ccc(cc4)C#N)n(C)c3c2)cc(C)c1N

InChI Key: InChIKey=SAEGMGKIJJCOSC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50450244
PNG
(CHEMBL4159730)
Show SMILES Cl.Cl.Cc1cc(Oc2ccc3nc(COc4ccc(cc4)C#N)n(C)c3c2)cc(C)c1N
Show InChI InChI=1S/C24H22N4O2/c1-15-10-20(11-16(2)24(15)26)30-19-8-9-21-22(12-19)28(3)23(27-21)14-29-18-6-4-17(13-25)5-7-18/h4-12H,14,26H2,1-3H3
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MMDB

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Article
PubMed
n/an/an/an/a 395n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay

Bioorg Med Chem 26: 5079-5098 (2018)


Article DOI: 10.1016/j.bmc.2018.09.006
BindingDB Entry DOI: 10.7270/Q2J968XC
More data for this
Ligand-Target Pair