null

SMILES: CCCCCCCN(CCCCCSc1[nH]cnc2nncc12)C(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=XYWZYKFEWQUCRK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50450327 (CHEMBL300518) Show SMILES CCCCCCCN(CCCCCSc1[nH]cnc2nncc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C24H32F2N6OS/c1-2-3-4-5-7-12-32(24(33)30-21-11-10-18(25)15-20(21)26)13-8-6-9-14-34-23-19-16-29-31-22(19)27-17-28-23/h10-11,15-17H,2-9,12-14H2,1H3,(H,30,33)(H,27,28,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay.				Bioorg Med Chem Lett 5: 167-72 (1995) BindingDB Entry DOI: 10.7270/Q2Z03833
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Mus musculus)	BDBM50450327 (CHEMBL300518) Show SMILES CCCCCCCN(CCCCCSc1[nH]cnc2nncc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C24H32F2N6OS/c1-2-3-4-5-7-12-32(24(33)30-21-11-10-18(25)15-20(21)26)13-8-6-9-14-34-23-19-16-29-31-22(19)27-17-28-23/h10-11,15-17H,2-9,12-14H2,1H3,(H,30,33)(H,27,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.				Bioorg Med Chem Lett 5: 167-72 (1995) BindingDB Entry DOI: 10.7270/Q2Z03833
					More data for this Ligand-Target Pair