BDBM50451086 CHEMBL4218996

SMILES: O=C(CN1C(=O)N[C@@]2(CCCc3ccccc23)C1=O)N1CCCCC1

InChI Key: InChIKey=NBXSXZQFQHXXQB-LJQANCHMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Major prion protein (Mesocricetus auratus)	BDBM50451086 (CHEMBL4218996) Show SMILES O=C(CN1C(=O)N[C@@]2(CCCc3ccccc23)C1=O)N1CCCCC1 |r| Show InChI InChI=1S/C19H23N3O3/c23-16(21-11-4-1-5-12-21)13-22-17(24)19(20-18(22)25)10-6-8-14-7-2-3-9-15(14)19/h2-3,7,9H,1,4-6,8,10-13H2,(H,20,25)/t19-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.17E+3	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blot				Bioorg Med Chem 25: 5875-5888 (2017) Article DOI: 10.1016/j.bmc.2017.09.024 BindingDB Entry DOI: 10.7270/Q2QR50Q1
					More data for this Ligand-Target Pair