BDBM50451498 CHEMBL536107

SMILES: Br.Oc1nc2cccc(C(NCc3ccccc3)P(O)(O)=O)c2nc1O

InChI Key: InChIKey=UKHCOMWRNHPTSH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50451498 (CHEMBL536107) Show SMILES Br.Oc1nc2cccc(C(NCc3ccccc3)P(O)(O)=O)c2nc1O Show InChI InChI=1S/C16H16N3O5P.BrH/c20-14-15(21)19-13-11(7-4-8-12(13)18-14)16(25(22,23)24)17-9-10-5-2-1-3-6-10;/h1-8,16-17H,9H2,(H,18,20)(H,19,21)(H2,22,23,24);1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus laevis oocyte expressing 1A/2B heteromeric human NMDA (hNMDA) receptor				Bioorg Med Chem Lett 12: 1099-102 (2002) BindingDB Entry DOI: 10.7270/Q24B31V2
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50451498 (CHEMBL536107) Show SMILES Br.Oc1nc2cccc(C(NCc3ccccc3)P(O)(O)=O)c2nc1O Show InChI InChI=1S/C16H16N3O5P.BrH/c20-14-15(21)19-13-11(7-4-8-12(13)18-14)16(25(22,23)24)17-9-10-5-2-1-3-6-10;/h1-8,16-17H,9H2,(H,18,20)(H,19,21)(H2,22,23,24);1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus laevis oocyte expressing 1A/2B heteromeric human NMDA (hNMDA) receptor				Bioorg Med Chem Lett 12: 1099-102 (2002) BindingDB Entry DOI: 10.7270/Q24B31V2
					More data for this Ligand-Target Pair