BDBM50451518 CHEMBL12256

SMILES: Oc1nc2cccc(C(NCCc3ccccc3)P(O)(O)=O)c2nc1O

InChI Key: InChIKey=HQJLJWGABWOSHH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50451518 (CHEMBL12256) Show SMILES Oc1nc2cccc(C(NCCc3ccccc3)P(O)(O)=O)c2nc1O Show InChI InChI=1S/C17H18N3O5P/c21-15-16(22)20-14-12(7-4-8-13(14)19-15)17(26(23,24)25)18-10-9-11-5-2-1-3-6-11/h1-8,17-18H,9-10H2,(H,19,21)(H,20,22)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus laevis oocyte expressing 1A/2A heteromeric human NMDA (hNMDA) receptor				Bioorg Med Chem Lett 12: 1099-102 (2002) BindingDB Entry DOI: 10.7270/Q24B31V2
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50451518 (CHEMBL12256) Show SMILES Oc1nc2cccc(C(NCCc3ccccc3)P(O)(O)=O)c2nc1O Show InChI InChI=1S/C17H18N3O5P/c21-15-16(22)20-14-12(7-4-8-13(14)19-15)17(26(23,24)25)18-10-9-11-5-2-1-3-6-11/h1-8,17-18H,9-10H2,(H,19,21)(H,20,22)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus laevis oocyte expressing 1A/2B heteromeric human NMDA (hNMDA) receptor				Bioorg Med Chem Lett 12: 1099-102 (2002) BindingDB Entry DOI: 10.7270/Q24B31V2
					More data for this Ligand-Target Pair