BDBM50451775 CHEMBL158510

SMILES: FC(F)(F)c1cccc(CNC(=N)\C=C\c2ccccc2)c1

InChI Key: InChIKey=QENHDVWRWPITTM-MDZDMXLPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50451775 (CHEMBL158510) Show SMILES FC(F)(F)c1cccc(CNC(=N)\C=C\c2ccccc2)c1 Show InChI InChI=1S/C17H15F3N2/c18-17(19,20)15-8-4-7-14(11-15)12-22-16(21)10-9-13-5-2-1-3-6-13/h1-11H,12H2,(H2,21,22)/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil binding to recombinant human NR1a/NR2B receptors expressed in L(tk-) cells				Bioorg Med Chem Lett 13: 693-6 (2003) BindingDB Entry DOI: 10.7270/Q2KK9D95
					More data for this Ligand-Target Pair