BDBM50452214 CHEMBL4214287

SMILES: Cn1ncc2c(NCc3ccccc3Cl)nc(Cl)nc12

InChI Key: InChIKey=SAXJHPQAOTWKBC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50452214 (CHEMBL4214287) Show SMILES Cn1ncc2c(NCc3ccccc3Cl)nc(Cl)nc12 Show InChI InChI=1S/C13H11Cl2N5/c1-20-12-9(7-17-20)11(18-13(15)19-12)16-6-8-4-2-3-5-10(8)14/h2-5,7H,6H2,1H3,(H,16,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Binding affinity to PDE2 (unknown origin) by SPR analysis				Bioorg Med Chem Lett 27: 5167-5171 (2017) Article DOI: 10.1016/j.bmcl.2017.10.054 BindingDB Entry DOI: 10.7270/Q28C9ZV3
					More data for this Ligand-Target Pair