BDBM50453014 CHEMBL4214846

SMILES: NC(=N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cc(cc2CCOc12)-c1cccc(CN2CCC(CC#N)CC2)c1)C(O)=O

InChI Key: InChIKey=CZRDKZHWMQNREJ-MHZLTWQESA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropilin-1 (Homo sapiens (Human))	BDBM50453014 (CHEMBL4214846) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cc(cc2CCOc12)-c1cccc(CN2CCC(CC#N)CC2)c1)C(O)=O |r| Show InChI InChI=1S/C33H39N7O6S2/c34-11-6-21-7-13-40(14-8-21)20-22-3-1-4-23(17-22)25-18-24-9-15-46-29(24)28(19-25)48(44,45)39-26-10-16-47-30(26)31(41)38-27(32(42)43)5-2-12-37-33(35)36/h1,3-4,10,16-19,21,27,39H,2,5-9,12-15,20H2,(H,38,41)(H,42,43)(H4,35,36,37)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a
NCE Discovery (Domainex Ltd Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...				J Med Chem 61: 4135-4154 (2018) Article DOI: 10.1021/acs.jmedchem.8b00210 BindingDB Entry DOI: 10.7270/Q2Q81GNK
					More data for this Ligand-Target Pair