BDBM50453055 CHEMBL72649

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1

InChI Key: InChIKey=MHWRZIBDNNXDFT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50453055 (CHEMBL72649) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1 Show InChI InChI=1S/C25H28F2N2O2/c26-21-5-3-19(4-6-21)24(30)2-1-9-28-10-12-29(13-11-28)17-18-14-20-16-22(27)7-8-23(20)25(31)15-18/h3-8,16,18H,1-2,9-15,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for the binding affinity towards 5-HT2 receptor measured by [3H]ketanserin binding to frontal cerebral cortex membranes of rat				Citation and Details BindingDB Entry DOI: 10.7270/Q2TB1912
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50453055 (CHEMBL72649) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1 Show InChI InChI=1S/C25H28F2N2O2/c26-21-5-3-19(4-6-21)24(30)2-1-9-28-10-12-29(13-11-28)17-18-14-20-16-22(27)7-8-23(20)25(31)15-18/h3-8,16,18H,1-2,9-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela Curated by ChEMBL					Assay Description Compound was evaluated for its affinity (pKi) to inhibit [3H]spiperone binding to the dopamine receptor D2				J Med Chem 34: 2242-7 (1991) Checked by Author BindingDB Entry DOI: 10.7270/Q2930VPR
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50453055 (CHEMBL72649) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1 Show InChI InChI=1S/C25H28F2N2O2/c26-21-5-3-19(4-6-21)24(30)2-1-9-28-10-12-29(13-11-28)17-18-14-20-16-22(27)7-8-23(20)25(31)15-18/h3-8,16,18H,1-2,9-15,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela Curated by ChEMBL					Assay Description Compound was evaluated for its affinity (pKi) to inhibit [3H]SCH-23390 binding to the dopamine receptor D1				J Med Chem 34: 2242-7 (1991) Checked by Author BindingDB Entry DOI: 10.7270/Q2930VPR
					More data for this Ligand-Target Pair