BindingDB logo
myBDB logout

null

SMILES: CCCCc1ccc(NC(=O)N2CCN(CC2)C(=O)c2cc(nc3ccccc23)-c2ccccc2)cc1

InChI Key: InChIKey=MNMUMVXHKLUJKW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454326   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50454326
PNG
(CHEMBL4217832)
Show SMILES CCCCc1ccc(NC(=O)N2CCN(CC2)C(=O)c2cc(nc3ccccc23)-c2ccccc2)cc1
Show InChI InChI=1S/C31H32N4O2/c1-2-3-9-23-14-16-25(17-15-23)32-31(37)35-20-18-34(19-21-35)30(36)27-22-29(24-10-5-4-6-11-24)33-28-13-8-7-12-26(27)28/h4-8,10-17,22H,2-3,9,18-21H2,1H3,(H,32,37)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps...

Bioorg Med Chem 26: 845-854 (2018)


Article DOI: 10.1016/j.bmc.2017.12.048
BindingDB Entry DOI: 10.7270/Q27S7RDV
More data for this
Ligand-Target Pair