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SMILES: Fc1ccccc1NC(=O)N1CCN(CC1)C(=O)c1cc(nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=LWESHBHAWYXJIH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454336   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50454336
PNG
(CHEMBL4217312)
Show SMILES Fc1ccccc1NC(=O)N1CCN(CC1)C(=O)c1cc(nc2ccccc12)-c1ccccc1
Show InChI InChI=1S/C27H23FN4O2/c28-22-11-5-7-13-24(22)30-27(34)32-16-14-31(15-17-32)26(33)21-18-25(19-8-2-1-3-9-19)29-23-12-6-4-10-20(21)23/h1-13,18H,14-17H2,(H,30,34)
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n/an/a 125n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps...

Bioorg Med Chem 26: 845-854 (2018)


Article DOI: 10.1016/j.bmc.2017.12.048
BindingDB Entry DOI: 10.7270/Q27S7RDV
More data for this
Ligand-Target Pair