BDBM50454351 CHEMBL4218953

SMILES: CCN(CC)c1ccc(NC(=O)N2CCN(CC2)C(=O)c2cc(nc3ccccc23)-c2ccccc2)cc1

InChI Key: InChIKey=OEROFEFUXGLYHM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50454351 (CHEMBL4218953) Show SMILES CCN(CC)c1ccc(NC(=O)N2CCN(CC2)C(=O)c2cc(nc3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C31H33N5O2/c1-3-34(4-2)25-16-14-24(15-17-25)32-31(38)36-20-18-35(19-21-36)30(37)27-22-29(23-10-6-5-7-11-23)33-28-13-9-8-12-26(27)28/h5-17,22H,3-4,18-21H2,1-2H3,(H,32,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps...				Bioorg Med Chem 26: 845-854 (2018) Article DOI: 10.1016/j.bmc.2017.12.048 BindingDB Entry DOI: 10.7270/Q27S7RDV
					More data for this Ligand-Target Pair