BDBM50454578 CHEMBL4203014
SMILES: [Na;v0+].[#8-]-[#6](=O)-c1cc(Cl)ccc1-[#7]-[#6](=O)-c1cccc(c1)-c1cnc2ccccc2c1
InChI Key: InChIKey=LBOIFUCSTNEHID-UHFFFAOYSA-M
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator inhibitor-1 (Homo sapiens (Human)) | BDBM50454578 (CHEMBL4203014) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hamari Chemicals, Ltd. Curated by ChEMBL | Assay Description Inhibition of human PAI-1 assessed as remaining enzyme activity by measuring p-nitroaniline release pre-incubated for 15 mins before 2 nM Spectrozyme... | Bioorg Med Chem Lett 28: 809-813 (2018) Article DOI: 10.1016/j.bmcl.2017.11.016 BindingDB Entry DOI: 10.7270/Q2TH8Q90 | |||||||||||
More data for this Ligand-Target Pair |