BDBM50454579 CHEMBL4215648

SMILES: OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)-c1cccc2ccccc12

InChI Key: InChIKey=FSAPKGGWSCLGCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50454579 (CHEMBL4215648) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)-c1cccc2ccccc12 Show InChI InChI=1S/C24H16ClNO3/c25-18-11-12-22(21(14-18)24(28)29)26-23(27)17-8-3-7-16(13-17)20-10-4-6-15-5-1-2-9-19(15)20/h1-14H,(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Hamari Chemicals, Ltd. Curated by ChEMBL					Assay Description Inhibition of human PAI-1 assessed as remaining enzyme activity by measuring p-nitroaniline release pre-incubated for 15 mins before 2 nM Spectrozyme...				Bioorg Med Chem Lett 28: 809-813 (2018) Article DOI: 10.1016/j.bmcl.2017.11.016 BindingDB Entry DOI: 10.7270/Q2TH8Q90
					More data for this Ligand-Target Pair