null
SMILES: Cc1ccc(NC(=O)Nc2cc(ccc2NC2CCCCC2)-c2ccccc2C(O)=O)cc1
InChI Key: InChIKey=CIAPSPYVIRZMQN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50454806 (CHEMBL4214458) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 504 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production pre-incubated for 1 hr followed by IFN-ga... | Bioorg Med Chem Lett 28: 732-736 (2018) Article DOI: 10.1016/j.bmcl.2018.01.010 BindingDB Entry DOI: 10.7270/Q28K7CP4 | |||||||||||
More data for this Ligand-Target Pair |