BindingDB logo
myBDB logout

null

SMILES: CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1C(=O)NS(=O)(=O)C(F)(F)F

InChI Key: InChIKey=HMIXLUCXVAYVRT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454812   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM50454812
PNG
(CHEMBL4208408)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1C(=O)NS(=O)(=O)C(F)(F)F
Show InChI InChI=1S/C30H35F3N4O4S/c1-19(2)17-37(18-20(3)4)27-15-12-22(16-26(27)35-29(39)34-23-13-10-21(5)11-14-23)24-8-6-7-9-25(24)28(38)36-42(40,41)30(31,32)33/h6-16,19-20H,17-18H2,1-5H3,(H,36,38)(H2,34,35,39)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production pre-incubated for 1 hr followed by IFN-ga...

Bioorg Med Chem Lett 28: 732-736 (2018)


Article DOI: 10.1016/j.bmcl.2018.01.010
BindingDB Entry DOI: 10.7270/Q28K7CP4
More data for this
Ligand-Target Pair