BDBM50455024 CHEMBL4205860

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCCN(C1=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=FEUALTSGLCXGEJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Homo sapiens (Human))	BDBM50455024 (CHEMBL4205860) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(C1=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H17F3N2O4S/c1-27-15-7-9-16(10-8-15)28(25,26)23-12-2-11-22(17(23)24)14-5-3-13(4-6-14)18(19,20)21/h3-10H,2,11-12H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Inhibition of Nox4 in HASMCs assessed as reduction in TGFbeta-induced increase in smooth muscle alpha actin level pretreated for 30 mins followed by ...				Bioorg Med Chem 26: 989-998 (2018) Article DOI: 10.1016/j.bmc.2017.12.023 BindingDB Entry DOI: 10.7270/Q2VD722W
					More data for this Ligand-Target Pair