BDBM50455391 CHEMBL4215240

SMILES: CCOC(=O)C1Cc2cc(OC)c(OC3CCCC3)cc2CN1C(=O)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=XUNGMDLLWCINPR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50455391 (CHEMBL4215240) Show SMILES CCOC(=O)C1Cc2cc(OC)c(OC3CCCC3)cc2CN1C(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H28F3NO6/c1-3-34-25(32)21-12-17-13-22(33-2)23(35-19-6-4-5-7-19)14-18(17)15-30(21)24(31)16-8-10-20(11-9-16)36-26(27,28)29/h8-11,13-14,19,21H,3-7,12,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50455391 (CHEMBL4215240) Show SMILES CCOC(=O)C1Cc2cc(OC)c(OC3CCCC3)cc2CN1C(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H28F3NO6/c1-3-34-25(32)21-12-17-13-22(33-2)23(35-19-6-4-5-7-19)14-18(17)15-30(21)24(31)16-8-10-20(11-9-16)36-26(27,28)29/h8-11,13-14,19,21H,3-7,12,15H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
					More data for this Ligand-Target Pair