BDBM50455395 CHEMBL4204765
SMILES: COc1cc2CCN(Cc2cc1OC1CCCC1)C(=O)c1ccc(Cl)cc1
InChI Key: InChIKey=XZOQUDHFZNEBST-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50455395 (CHEMBL4204765) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins | Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50455395 (CHEMBL4204765) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins | Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS | |||||||||||
More data for this Ligand-Target Pair |