BDBM50455396 CHEMBL4211564

SMILES: COc1ccc(cc1OC)C(=O)N1CCc2cc(OC)c(OC3CCCC3)cc2C1

InChI Key: InChIKey=RMJXOMAZYWSGCX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50455396 (CHEMBL4211564) Show SMILES COc1ccc(cc1OC)C(=O)N1CCc2cc(OC)c(OC3CCCC3)cc2C1 Show InChI InChI=1S/C24H29NO5/c1-27-20-9-8-17(13-21(20)28-2)24(26)25-11-10-16-12-22(29-3)23(14-18(16)15-25)30-19-6-4-5-7-19/h8-9,12-14,19H,4-7,10-11,15H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50455396 (CHEMBL4211564) Show SMILES COc1ccc(cc1OC)C(=O)N1CCc2cc(OC)c(OC3CCCC3)cc2C1 Show InChI InChI=1S/C24H29NO5/c1-27-20-9-8-17(13-21(20)28-2)24(26)25-11-10-16-12-22(29-3)23(14-18(16)15-25)30-19-6-4-5-7-19/h8-9,12-14,19H,4-7,10-11,15H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
					More data for this Ligand-Target Pair